Some skin doesn’t call for drastic changes — just a clearly visible improvement in quality.
Smoothness.
Glow.
Evenness.
The Signature combination of SkinPen microneedling and ZO Skin Booster is designed for exactly that result — the union of controlled biostimulation and targeted dermal hydration.
SkinPen triggers the process of percutaneous collagen induction (CIT), creating microchannels and activating fibroblasts. This kicks off neocollagenesis and remodelling of the extracellular matrix.
The ZO Skin Booster, applied immediately afterwards, uses these microchannels to act deeply on the skin — delivering intensive hydration, improved texture and a strengthened skin barrier.
The result is what patients often describe as:
→ “skin that looks healthy, clean and fresh”
→ no volume, no artificial effect — but with clearly visible quality
At our clinic this treatment isn’t just aesthetic — it’s a dermatologically guided skin-quality therapy.
How is the treatment performed?
The treatment begins with SkinPen microneedling, creating precisely controlled micro-perforations in the epidermis and dermis, depending on the indication.
This activates:
- fibroblasts
- synthesis of type I and type III collagen
- regeneration of the dermal matrix
The ZO Skin Booster is then applied; it penetrates the skin via the microchannels and acts on:
- deep hydration
- renewal of the skin barrier
- improved skin texture and glow
This combination delivers both an immediate and a long-term effect.
To further amplify results, the treatment is often included in wider protocols:
- with Morpheus8 for deeper stimulation and skin firming
- with the CO2 Smaxel laser for more pronounced regeneration and texture
- with Candela Nordlys for pigmentation and skin tone evenness
- with HIFU for lifting and action on deeper layers
- with PRP and Angel PRP (Arthrex) for regeneration
- with exosomes for enhanced biostimulation
- with polynucleotides for long-term renewal of the dermis
Who is the treatment for?
This combination is ideal for patients who want:
- to improve skin quality and texture
- to achieve a “glass skin” effect (smooth, glowing, even skin)
- to reduce the visibility of pores
- to soften fine lines
- to restore freshness and hydration
It is a particularly good choice for:
- dehydrated, tired skin
- dull skin
- people who want a natural result without volumisation
- patients who want a visible effect with minimal downtime
When are results visible?
The first effect is visible very quickly:
- hydration
- glow effect
- a fresher look
But the real result comes over the following weeks, as the following are activated:
- neocollagenesis
- regeneration of the dermis
Over time the skin becomes:
- smoother
- firmer
- more even
Recovery and precautions
After the treatment, the following are possible:
- redness
- mild sensitivity
- a tight feeling
Recovery is short — typically 1–2 days.
We recommend:
- avoiding sun exposure and using SPF
- avoiding active products for a few days
- avoiding heat and physical activity for 24–48 hours
Preparing for the treatment
Before the treatment a topical anaesthetic cream is applied to make the procedure as comfortable as possible.
Recommendations:
- avoid alcohol before the treatment
- avoid medications that increase the tendency to bruise
- don’t arrive with active inflammation on the skin
Our approach
At our clinic this isn’t a generic “skin glow treatment” — it’s part of an individually planned dermatological protocol.
Treatments are delivered by experienced dermatology specialists, with detailed skin analysis and precise planning.
Our approach is built on:
- understanding the skin
- correct indication
- time devoted to the patient
Because the best result isn’t only visible — it’s also safe, natural and sustainable over the long term.
Price:
For detailed information on payment options and treatment prices, please refer to the current price list of Poliklinika dr. Jelena Jakić.
