Signature SkinPen + NCTC

Not all skin is the same — and not all skin responds to stimulation in the same way.

For some, regeneration needs to be triggered.
For others — the skin first needs to be given the “material” to renew itself at all.

This is exactly where the combination of SkinPen microneedling and the NCTC cocktail comes into its own.

SkinPen triggers the process of controlled micro-trauma and neocollagenesis, activating fibroblasts and the skin’s regenerative mechanisms.
NCTC (New Cellular Treatment Concept) acts on the other side — as a complex of amino acids, vitamins, coenzymes and nucleotides that gives the skin what it often lacks: biological building blocks for regeneration.

In other words — we don’t only signal the skin to renew itself; we give it the resources to do so well.

The result is skin that doesn’t just look fresher; it appears hydrated, nourished and functionally renewed.

This combination is particularly powerful on skin that is exhausted, dehydrated or under chronic stress — when stimulation alone isn’t enough.


How is the treatment performed?

The treatment begins with SkinPen microneedling, creating precisely controlled micro-perforations in the skin, depending on the indication and the area being treated.

This activates:

  • fibroblasts
  • collagen and elastin synthesis
  • regeneration of the dermal matrix

The NCTC cocktail is then applied; it penetrates the skin via the microchannels and acts on:

  • cellular metabolism
  • hydration
  • the skin’s regenerative potential

This combination enables better absorption of active ingredients and an enhanced therapeutic effect.

For further results, the treatment is often combined with:

  • Morpheus8 for deeper stimulation and skin tightening
  • CO2 Smaxel laser for texture and regeneration
  • Candela Nordlys for pigmentation and skin tone quality
  • HIFU for a lifting effect and action on deeper layers
  • PRP and Angel PRP (Arthrex) for additional regeneration
  • exosomes for strong biological stimulation
  • polynucleotides for renewal of the dermis

Who is the treatment for?

This combination is particularly indicated for:

  • dehydrated, exhausted skin
  • skin with loss of glow and vitality
  • early signs of ageing
  • uneven texture and enlarged pores
  • skin exposed to stress, fatigue and external factors
  • patients who want a natural improvement without volumisation

Ideal for those who feel their skin is “out of balance” — and needs both stimulation and nutritional support.


When are results visible?

The first effect is visible relatively quickly:

  • better hydration
  • a fresher look
  • a subtle glow effect

But the real result comes gradually, through regeneration of the dermis and improved cellular function.

Over time the skin becomes:

  • more elastic
  • smoother
  • more even
  • more resilient

Recovery and precautions

After the treatment, the following are possible:

  • redness
  • mild sensitivity
  • slight swelling

Recovery is short — typically 1–2 days.

We recommend:

  • avoiding sun exposure and using SPF
  • avoiding active products for a few days
  • avoiding heat and exercise for 24–48 hours

Preparing for the treatment

Before the treatment a topical anaesthetic cream is applied to make the procedure as comfortable as possible.

We recommend:

  • not consuming alcohol before the treatment
  • avoiding medications that increase the tendency to bruise
  • arriving without active inflammatory processes on the skin

Our approach

At our clinic these treatments aren’t pre-defined protocols — they are the outcome of an individual dermatological assessment.

Treatments are delivered by experienced dermatology specialists, with detailed planning and follow-up.

We give patients what makes the biggest difference in aesthetic medicine:

  • time
  • professional knowledge
  • a clear plan

Because real reassurance comes from the feeling that the treatment is tailored specifically to you.

Price: 

For detailed information on payment options and treatment prices, please refer to the current price list of Poliklinika dr. Jelena Jakić.

Contact Us

Have a question? Send us an enquiry and we will be happy to respond.

    Need Help?

    Our team of specialists is at your disposal for all information and advice.
    Phone

    +385 1 2365 953
    +385 91 9117 093

    Email

    info@poliklinika-jakic.hr

    FAQ

    Frequently asked questions

    Here you’ll find answers to the questions our clients most often ask about our services and treatments.

    + What does the SkinPen microneedling and NCTF combination involve?
    This combination pairs mechanical skin stimulation through microneedling with a rich cocktail of active ingredients (vitamins, amino acids, antioxidants) delivered via NCTF. The skin is given both a regenerative trigger and the nutrients it needs at the same time.
    + What are the main advantages of this treatment?
    Improved hydration, more even texture, better skin glow and accelerated regeneration — the result is skin that looks healthier and more vital.
    + Which skin condition is this treatment best suited to?
    Dehydrated, tired, dull skin and the early signs of ageing.
    + When are results visible?
    The skin already looks fresher after the first treatment, while the full effect develops over a series of sessions.
    + How many treatments are needed?
    A series of treatments is recommended for an optimal, long-lasting result.
    + Is the treatment painful?
    Minimally uncomfortable, with a topical anaesthetic cream applied beforehand.
    + Why is this combination popular with patients?
    Because it delivers a visible “glow effect” alongside an improvement in skin quality — an ideal combination for those who want both an immediate and a long-term result.