The skin renews itself naturally — but over time that process becomes slower, more uneven and less efficient.
The result is:
uneven complexion,
pigmentation,
enlarged pores,
fine lines.
Chemical peels address precisely this problem — but not superficially, rather in a controlled and medically precise way.
These are treatments that use various acids (AHA, BHA, TCA and others) to stimulate exfoliation, regeneration of the epidermis and stimulation of the dermis, gradually renewing the skin and restoring its balance.
What makes them exceptionally valuable is their adaptability — the intensity, depth and type of peel are selected according to the specific skin and indication.
At our clinic, a chemical peel is not a single, off-the-shelf treatment but a dermatologist-led skin therapy.
How is the treatment performed?
The treatment begins with skin preparation, after which the chosen chemical solution is applied; it works at a defined depth — from superficial (epidermis) to medium-deep (dermis).
Depending on the type of peel, the following are achieved:
- exfoliation of dead cells
- stimulation of cellular renewal
- regulation of sebum
- lightening of pigmentation
- improved skin texture
The duration and intensity are carefully controlled, after which the skin is neutralised and soothed.
For optimal results, chemical peels are often combined with:
- Candela Nordlys (IPL/Frax) for pigmentation and evening out skin tone
- CO2 Smaxel (Soft Glow) for additional regeneration
- Morpheus8 for skin firming and structure
- Icoone Laser Med for microcirculation and recovery
- SkinPen microneedling for skin texture
- PRP and Angel PRP (Arthrex) for regeneration
- exosomes and polynucleotides for biostimulation
Who is the treatment for?
Chemical peels are ideal for patients who wish to address:
- uneven complexion
- pigmentation and melasma
- acne and oily skin
- enlarged pores
- fine lines
- signs of photoageing
They are particularly suitable for:
- younger patients as a therapy for acne and excess sebum
- patients seeking a gradual improvement in their skin
- those who want a clean-skin effect without invasive treatments
When are results visible?
Results depend on the type of peel.
- superficial peels → freshness and glow very quickly
- medium-depth peels → more visible results within a few days
Optimal effect is achieved through a series of treatments.
Over time, the skin becomes:
- smoother
- cleaner
- more even
- healthier
Recovery and precautions
Recovery varies depending on the intensity of the peel.
Possible reactions include:
- redness
- tightness
- flaking of the skin
With milder peels, recovery is minimal, while with stronger peels it may last several days.
We recommend:
- strict SPF protection
- avoiding sun exposure
- avoiding active skincare products
- proper skin hydration
Preparing for the treatment
Before the treatment:
- a skin-priming routine (skincare protocol) may be recommended
- avoid retinol and acids for several days beforehand
- do not attend with irritated or inflamed skin
Anaesthetic cream is not usually required.
Our approach
At our clinic, chemical peels are not standard cosmetic treatments.
They are performed by experienced dermatology specialists, with:
- a precise skin assessment
- individual selection of acid and concentration
- a treatment plan over time
Because true results do not come from a single peel — they come from the right strategy.
For our patients, we provide:
- safety
- expert guidance
- results that look natural
MESOESTETIC® CHEMICAL PEELS — next-generation, medically controlled skin renewal
There are peels — and then there are those developed as dermatological therapies with clearly defined indications and protocols.
Mesoestetic® chemical peels belong to the latter.
They are professional medical formulations that combine various acids (AHA, BHA, TCA and specific depigmentation complexes) to act in a targeted way on specific skin concerns — from pigmentation and acne to signs of ageing.
What sets them apart is not only their composition — but the precision and predictability of their results.
They work through:
- controlled exfoliation of the epidermis
- stimulation of cellular renewal
- regulation of sebum
- modulation of melanogenesis (pigmentation)
- improved skin structure and quality
The result is not just glow, but skin that is more even, more stable and functionally better.
At our clinic, a Mesoestetic peel is not a one-off treatment — it is part of an individually planned dermatological skin therapy.
How is the treatment performed?
The treatment begins with thorough skin preparation, after which the selected Mesoestetic® peel is applied according to a precisely defined indication.
Depending on the type of peel (e.g. depigmenting, anti-ageing, acne), it acts at different levels of the skin:
- epidermis → exfoliation and renewal
- dermis → stimulation of fibroblasts and collagen
During the treatment, you may feel:
- warmth
- mild tingling
After a defined period, the peel is neutralised and the skin is soothed.
Cosmelan® — the most renowned medical treatment for pigmentation
Pigmentation is more than an aesthetic concern.
It is a sign of disruption in the process of melanogenesis — the complex mechanism by which pigment is produced in the skin.
That is why simply lightening it is rarely enough — pigmentation needs to be controlled at the level of its cause.
Cosmelan® is precisely such a treatment.
It is one of the most renowned and effective depigmentation protocols in aesthetic dermatology, working through inhibition of the enzyme tyrosinase, which is key to the formation of melanin.
This means we don’t only treat existing pigmentation — we also address its formation in the future.
The result is skin that becomes:
- visibly more even
- brighter
- more stable in pigmentation
What sets Cosmelan® apart is the fact that it is not a single treatment — it is a structured therapeutic process, carried out in stages.
At our clinic, Cosmelan is not a quick fix; it is a medically led pigmentation therapy with a long-term goal.
How is the treatment performed?
The treatment consists of two key phases:
1. Professional in-clinic phase
The Cosmelan® mask is applied to the skin and left on for a defined period (according to individual assessment), after which the patient continues the therapy at home.
2. Home therapy (the key to success)
The patient uses specific Cosmelan® products that:
- regulate melanogenesis
- prevent the return of pigmentation
- maintain the result
The action of the treatment includes:
- exfoliation of the epidermis
- inhibition of tyrosinase
- regulation of melanocyte activity
For optimal results, Cosmelan® is often combined with:
- Candela Nordlys (IPL) for additional action on pigmentation
- Candela Frax for skin texture and quality
- CO2 Smaxel (Soft Glow) for regeneration
- Morpheus8 for structure and firming
- Icoone Laser Med for recovery and microcirculation
- PRP and Angel PRP (Arthrex) for regeneration
- exosomes and polynucleotides for skin stabilisation
Who is the treatment for?
Cosmelan® is particularly indicated for:
- melasma (hormonal pigmentation)
- sun spots
- post-inflammatory hyperpigmentation (e.g. following acne)
- uneven complexion
Ideal candidates are patients who:
- have persistent pigmentation that keeps returning
- want a long-term solution rather than a short-lived effect
- are willing to follow the therapeutic protocol
When are results visible?
The first results are visible relatively quickly:
- lightening of pigmentation
- a more even complexion
However, the true result develops through:
- several weeks
- stabilisation of melanogenesis
Over time, the skin becomes:
- brighter
- more even
- more stable
Recovery and precautions
Cosmelan® involves an expected skin reaction — and that is part of the therapy.
Possible reactions include:
- redness
- tightness
- flaking
- a sensation of warmth
These reactions are temporary and form part of the skin renewal process.
Key measures:
- strict SPF protection
- regular at-home care according to the protocol
- avoiding sun exposure
Preparing for the treatment
Before the treatment:
- a dermatological skin assessment is carried out
- a preparatory skincare routine may be introduced where appropriate
Recommendations:
- do not attend with irritated skin
- avoid active skincare products before the treatment
- follow your doctor’s instructions
Anaesthetic cream is not required.
Our approach
Cosmelan® requires expertise and close monitoring.
At our clinic, the treatment is led by experienced dermatology specialists, with:
- a precise diagnosis of the pigmentation
- individual treatment planning
- continuous monitoring throughout the entire process
For our patients, we provide what is crucial in this treatment:
- clear guidance
- support through every stage
- a sense of safety
Because the success of Cosmelan therapy depends not only on the treatment itself — but on the way in which it is delivered.
Dermamelan® — a medical solution for stubborn and deep pigmentation
There is pigmentation that can be eased.
And pigmentation that keeps returning — regardless of the treatments applied.
Dermamelan® was developed precisely for the latter group.
It is an advanced medical depigmentation protocol that acts on deeper layers of the skin and more complex disturbances of melanogenesis, where conventional treatments often deliver only limited results.
Unlike superficial approaches, Dermamelan® works through:
- inhibition of tyrosinase and other key enzymes of melanogenesis
- regulation of melanocyte activity
- reduction of melanin synthesis
- controlling the recurrence of pigmentation
This means we don’t just treat visible pigmentation — we also address its underlying cause.
The result is skin that becomes:
- visibly more even
- brighter
- more stable in the long term
Dermamelan® is not an aesthetic treatment — it is a medical pigmentation therapy.
At our clinic it is used in patients who require a structured, long-term and controlled approach.
How is the treatment performed?
The Dermamelan® protocol consists of several phases:
1. Professional in-clinic phase
The Dermamelan® mask is applied to the skin and acts on its deeper layers, remaining in place for a defined period in line with individual assessment.
2. Home therapy (the key phase)
The patient continues the therapy at home using specially formulated products that:
- inhibit melanogenesis
- stabilise melanocytes
- prevent the return of pigmentation
The action includes:
- controlled exfoliation
- biochemical regulation of pigment
- long-term stabilisation of the skin
For optimal results, Dermamelan® is often combined with:
- Candela Nordlys (IPL) for additional action on pigmentation
- Candela Frax for skin texture and quality
- CO2 Smaxel (Soft Glow / Radiant Renewal) for regeneration
- Morpheus8 for structure and firming
- Icoone Laser Med for recovery and microcirculation
- PRP and Angel PRP (Arthrex) for regeneration
- exosomes and polynucleotides for skin stabilisation
Who is the treatment for?
Dermamelan® is indicated for:
- stubborn melasma
- deep and resistant pigmentation
- pigmentation that returns following other treatments
- post-inflammatory hyperpigmentation
Ideal candidates are patients who:
- have already tried other treatments without lasting results
- want a long-term solution
- are willing to follow the therapeutic protocol
This is a treatment for more demanding cases — and for that reason it requires a precise indication.
When are results visible?
The first results are visible relatively quickly:
- lightening of pigmentation
- a more even complexion
However, the true result develops through:
- several weeks
- stabilisation of melanogenesis
Over time, the skin becomes:
- brighter
- more even
- more stable
Recovery and precautions
Dermamelan® involves a more pronounced skin reaction — which is expected and forms part of the therapy.
Possible reactions include:
- redness
- flaking
- a tingling sensation
- tightness
Recovery is individual and may last from a few days to longer, depending on the skin.
Key measures:
- strict SPF protection
- regular at-home care
- avoiding sun exposure
- following all instructions from your doctor
Preparing for the treatment
Before the treatment we carry out:
- a thorough dermatological assessment
- a treatment plan
Recommendations:
- avoid active skincare products before the treatment
- do not attend with irritated skin
- prepare your skin in line with your doctor’s instructions
Anaesthetic cream is not required.
Our approach
Dermamelan® requires experience, careful monitoring and an individual approach.
At our clinic the therapy is led by experienced dermatology specialists, with:
- a precise diagnosis of the pigmentation
- individual treatment planning
- continuous monitoring through every stage
For our patients, we provide what is crucial in treatments such as these:
- clear guidance
- support
- a sense of safety
Because the success of Dermamelan therapy depends not only on the product itself — but on expert guidance throughout the entire process.
ACNELAN — A PROFESSIONAL TREATMENT FOR ACNE AND OILY SKIN
Acne is more than an aesthetic concern.
It is the result of complex processes within the skin — increased sebum production, hyperkeratinisation, bacterial activity and an inflammatory response.
That is why it cannot be resolved by any single approach.
Acnelan® was developed as a comprehensive dermatological protocol for controlling acne and regulating oily skin, acting simultaneously on several key mechanisms.
Its action includes:
- regulation of sebum
- reduction of inflammation
- normalisation of keratinisation
- an antibacterial effect
- prevention of new lesions
In other words — it does not only treat the consequences, but also the cause of acne.
The result is skin that becomes:
- cleaner
- calmer
- less oily
- more stable in the long term
At our clinic, Acnelan is not a facial treatment — it is a medically led acne therapy.
How is the treatment performed?
Acnelan® is delivered in two key phases:
1. Professional in-clinic phase
A specific medical formulation is applied to the skin, acting on:
- sebum regulation
- exfoliation
- antibacterial action
During the treatment, you may feel a mild tingling or warmth.
2. Home therapy (the key to success)
The patient continues the therapy at home using specially formulated products that:
- control sebum production
- prevent the formation of new acne
- maintain the result
For optimal results, Acnelan is often combined with:
- Candela Nordlys (IPL) for inflammatory components and redness
- Candela Frax for scarring and skin texture
- CO2 Smaxel (Soft Glow) for skin regeneration following acne
- Morpheus8 for scarring and skin structure
- Icoone Laser Med for reducing inflammation and improving circulation
- SkinPen microneedling for post-acne scarring
- PRP for regeneration
- polynucleotides for skin renewal
Who is the treatment for?
Acnelan® is indicated for:
- active acne (mild to moderate)
- oily and seborrhoeic skin
- blocked pores and comedones
- post-acne conditions
Ideal candidates are patients who:
- suffer from persistent acne
- want a medically led solution
- are looking for long-term skin control
When are results visible?
The first results may be visible relatively quickly:
- reduced skin oiliness
- reduction of inflammatory lesions
However, the true result develops through:
- several weeks
- stabilisation of sebum and skin
The skin becomes:
- cleaner
- calmer
- more balanced
Recovery and precautions
Following the treatment, possible reactions include:
- redness
- flaking
- a sensation of tightness
These reactions are temporary and form part of the therapeutic process.
We recommend:
- avoiding sun exposure
- SPF protection
- appropriate at-home care
- avoiding aggressive skincare products
Preparing for the treatment
Before the treatment:
- a dermatological assessment is carried out
- a preparatory skincare routine may be introduced where appropriate
Recommendations:
- do not attend with irritated skin
- avoid active skincare products for several days beforehand
Anaesthetic cream is not required.
Our approach
Acne requires a serious and systematic approach.
At our clinic, Acnelan therapy is led by experienced dermatology specialists, with:
- a precise diagnosis of the type of acne
- individual treatment planning
- continuous monitoring
For our patients we provide what matters most:
- clear guidance
- realistic expectations
- support throughout the entire process
Because treating acne is not a single treatment — it is a process that requires expertise and patience.
1. Treatment — Deep cleansing and sebum balance
The first treatment focuses on cleansing and unclogging the pores. An exfoliant containing salicylic and mandelic acid is used, removing dead cells and reducing congestion. Following the very first treatment, there is a noticeable reduction in oiliness and inflammation.
2. Treatment — Regulation and skin renewal
The second treatment further reduces existing lesions and stimulates renewal of the epidermis. Active ingredients act in a targeted way on the bacteria associated with acne, while a hydrating complex helps prevent irritation and dryness.
3. Treatment — Stabilisation and prevention of recurrence
The third treatment strengthens the skin barrier, stabilises sebum levels and provides a long-lasting effect. The skin becomes visibly cleaner, smoother and less prone to new breakouts. Combined with proper at-home care, the results are long-lasting and stable.
Other Mesoestetic® peels:
Mesopeel® MC Lactic 30%
A peel based on lactic acid, ideal for hydrating dry and dehydrated skin. It encourages moisture retention in the skin and gives it a radiant, healthy appearance. It evens out the complexion and improves skin texture. Suitable for sensitive and mature skin.
Mesopeel® MD Salicylic 20%
Formulated for oily, acne-prone skin with enlarged pores. Salicylic acid penetrates deeply into the pores, removing excess sebum and impurities. It helps prevent new breakouts and inflammation, and acts in an anti-inflammatory and keratolytic way.
Mesopeel® MD Retiflash
A powerful regenerating peel that revitalises tired, lacklustre skin. It delivers an intense glow effect and improves skin tone. It softens fine lines, irregularities and signs of fatigue. Ideal for stimulating skin renewal and evening out the complexion.
Mesopeel® MD phenTCA
An anti-ageing peel for treating signs of advanced ageing, scarring and deep lines. The combination of TCA and phenol delivers deep skin regeneration. It firms the skin and stimulates collagen production. Results include visibly smoother and rejuvenated skin.
Mesopeel® MD Periocular
A specialised peel for the delicate eye area. It softens fine lines, dark circles and shadows beneath the eyes. It boosts microcirculation and brings freshness back to the gaze. A gentle yet effective formula suited to the thin skin of this area.
Mesopeel® MD Oxyage
A retexturising peel that cleanses the skin and removes surface irregularities. An ideal solution for skin with uneven texture and a tired appearance. It renews the surface layer of the skin and brings freshness back. Also suitable for more sensitive skin.
Mesopeel® MD Melanostop Tran3x
A depigmenting peel that targets uneven skin tone and pigmentation marks. It regulates melanogenesis and reduces existing hyperpigmentation. It evens out the complexion and improves skin radiance. Ideal for treating melasma and sun spots.
Mesopeel® MD Melanoplus Touch
A peel for targeted treatment of localised dark spots. It works powerfully on areas of pronounced hyperpigmentation. It brightens the skin and helps reduce stubborn pigmentation. Can be used on its own or as an addition to other treatments.
Mesopeel® MD Mandelic 30%
Contains 30% mandelic acid, ideal for oily and pigmented skin. It regulates sebum production, tightens pores and acts antibacterially. It lightens hyperpigmentation and improves the complexion without causing irritation. Also suitable for more sensitive skin.
Mesopeel® MD Blemiskin
A peel with keratolytic and antibacterial action, specially formulated for acne. It removes dead skin cells, decongests the pores and reduces inflammation. It softens irregularities and helps prevent their recurrence. The skin becomes cleaner and smoother.
Mesopeel® MD Azelan RX
A peel containing azelaic acid, perfect for sensitive and reactive skin. It calms redness, soothes inflammation and acts against acne. It also addresses pigmentation with minimal irritation. An ideal solution for couperose and rosacea.
OTHER PEELS AVAILABLE AT OUR CLINIC:
TCA peel (trichloroacetic acid)
The TCA peel is a medium-depth chemical peel that addresses lines, hyperpigmentation, acne scarring and uneven skin texture. In controlled concentrations, TCA stimulates skin regeneration and the synthesis of collagen.
We offer:
- TCA cross (for scarring and deep pores)
- TCA face, back, décolletage
- TCA localised (e.g. around the eyes, partial, less than 5 cm)
- TCA on the limbs (upper arms, forearms, thighs, lower legs)
It is ideal for treating photoageing, keratoses, superficial scarring and fine lines.
For deep renewal and an anti-ageing effect, medical peels contain multi-layered acids, retinoids or stimulators of dermal activity, and are often used in combination with other treatments (PRP, microneedling).
Available options include:
- Jessner peel — a classic anti-ageing peel combining salicylic acid, lactic acid and resorcinol
- Pixell peeling — a combination of SkinPen microneedling and TCA peel (deep renewal)
- Peel booster — an additional layer used in combined treatments
REVITALISING PEEL — PRX T33
PRX-T33 is a bio-revitalising peel without exfoliation, using a combination of TCA acid and hydrogen peroxide, which acts in the deeper layers of the skin without flaking, and delivers:
- tightening and a lifting effect
- increased skin density
- smoothing of lines and pores
- immediate radiance and regeneration
PRX is perfect for those who want visible results with no downtime.
Price
Prices vary depending on the type of peel, the area of skin treated and the combination of treatments required.
For detailed information on payment options and treatment prices, please refer to the current price list of Poliklinika dr. Jelena Jakić.
