Facial mesotherapy

Treatment overview

The skin doesn’t lose quality all at once — it does so gradually, through reduced hydration, slower regeneration and a drop in collagen production. The result is a tired look, loss of glow and the feeling that the skin no longer “responds” the way it used to.

Facial mesotherapy is one of the most natural and precise ways to revitalise the skin — a treatment that delivers active substances directly into the middle layer of the skin, exactly where they are needed.

A combination of hyaluronic acid, vitamins, amino acids and antioxidants enables:

  • deep hydration
  • encouragement of regeneration
  • improved tone and elasticity
  • restored freshness and glow

What makes mesotherapy special is that it doesn’t act on the surface — it “nourishes the skin from within”, stimulating its natural processes.

Mesotherapy has been used in medicine for decades and has become a foundational treatment in aesthetic dermatology for maintaining skin quality, particularly as a preventive measure against ageing.

Patients often arrive with a familiar but rarely voiced feeling — that the skin looks tired, lifeless or “without energy”, regardless of the products they’re using.

It shows up in the mirror in the morning, in photographs and in everyday interactions, when the face doesn’t reflect the freshness you feel.

In social and professional settings, fresh, healthy-looking skin signals energy, polish and self-confidence — while tired skin can leave the opposite impression.

Mesotherapy doesn’t change the face — it restores skin quality in a way that looks natural, subtle and lasting.


How the treatment is performed

The treatment is delivered through micro-injections into the surface and middle layers of the skin.

During the procedure:

  • the condition of the skin is assessed
  • a cocktail of active ingredients is selected
  • the product is administered into the targeted zones

The procedure is quick and tailored to the skin’s individual needs.


Who the treatment is for

The treatment is ideal for people who:

  • have dehydrated or tired skin
  • want to improve skin quality and glow
  • want to act preventively against ageing
  • want a natural result without volume or change in contour

Suitable for all skin types and age groups.


Our approach

With mesotherapy the key isn’t the treatment itself — it’s the right choice of active ingredients.

At our clinic every treatment starts with a skin assessment, on the basis of which we choose a cocktail that has a real effect.

We don’t use one-size-fits-all formulas.

We tailor the therapy to your skin, your needs and your goals.

We take time over the explanation — because we want you to understand the process and the result.

Patients often notice that their skin looks fresher, healthier and more “alive” — without dramatic change.


Preparing for the treatment

Before the treatment, we recommend:

  • arriving with clean skin
  • avoiding aggressive treatments for a few days beforehand
  • letting your doctor know about any medication you’re taking

A topical anaesthetic cream may be used where needed.


Recovery and precautions

Recovery is minimal.

After the treatment:

  • mild redness may occur
  • tiny marks may appear at the injection points

Recommendations:

  • avoid sun exposure and use SPF
  • don’t apply aggressive products

When results become visible

Results are visible after the very first treatment.

  • best effect over a series of treatments
  • long-term improvement in skin quality

Outcome:

  • hydrated skin
  • better tone
  • a fresh, healthy look

Treatment combinations

For maximum revitalising effect:

  • Candela Nordlys — for skin tone quality and pigmentation
  • CO2 Smaxel — for skin regeneration
  • Morpheus8 — for collagen and tightening
  • HIFU — for lifting
  • Icoone Laser Med — for microcirculation

Additionally:

  • PRP treatments
  • individualised dermocosmetics

All combinations are planned individually — according to the skin’s needs.

Price

For detailed information on payment options and treatment prices, please refer to the current price list of Poliklinika dr. Jelena Jakić.

Contact Us

Have a question? Send us an enquiry and we will be happy to respond.

    Need Help?

    Our team of specialists is at your disposal for all information and advice.
    Phone

    +385 1 2365 953
    +385 91 9117 093

    Email

    info@poliklinika-jakic.hr

    FAQ

    Frequently asked questions

    Here you’ll find answers to the questions our clients most often ask about our services and treatments.

    + What is facial mesotherapy and how does it work?
    Mesotherapy is a minimally invasive treatment in which active ingredients such as hyaluronic acid, vitamins, minerals and amino acids are delivered into the surface layers of the skin. The skin is given exactly what it lacks, encouraging hydration, regeneration and renewal.
    + Which problems can mesotherapy improve?
    It is particularly effective for dehydrated skin, loss of glow, fine lines and the early signs of ageing. It is often used as the first step in an anti-ageing approach because it improves skin quality from within.
    + When are results visible?
    After the very first treatment the skin already looks fresher and more hydrated, while the full effect develops over a series of treatments.
    + How many treatments are needed?
    A series of several treatments is usually recommended, tailored to the condition of the skin and the desired result.
    + Is the treatment painful?
    Discomfort is minimal and short-lived, and a topical anaesthetic cream can be used.
    + Is there any recovery after the treatment?
    A mild, transient skin reaction is possible, but most patients return to everyday activities very quickly.
    + Why is mesotherapy often part of a long-term skincare plan?
    Because it doesn’t just deliver an immediate effect; it continuously improves skin quality — which is exactly why it is often included in personalised skincare protocols.