There are moments when the skin needs more than a single treatment.
Not just stimulation.
Not just hydration.
But coordinated regeneration at the cellular level.
The combination of SkinPen microneedling and exosomes delivers exactly that approach — controlled skin stimulation paired with targeted biological regeneration.
SkinPen triggers the process of percutaneous collagen induction, creating microchannels and activating the skin’s natural regenerative response. At the same time, exosomes — carriers of bioactive signals — act at the level of cellular communication, further amplifying renewal, reducing the inflammatory response and optimising regeneration of the dermis.
In other words, we don’t just signal the skin to renew itself — we give it “instructions” on how to do it better.
The result is skin that doesn’t just look fresher, but is structurally higher quality, more resilient and more vital.
At our clinic this combination is not a standard protocol but part of an individually planned therapy.
Because the difference isn’t in what we do — but how, when and for whom.
How is the treatment performed?
The treatment begins with SkinPen microneedling, creating precisely controlled micro-perforations in the epidermis and dermis.
This activates:
- fibroblasts
- the neocollagenesis process
- remodelling of the extracellular matrix
Immediately afterwards, exosomes are applied; they penetrate the skin via the microchannels and act on:
- cellular signalling
- tissue regeneration
- modulation of the inflammatory response
This sequential approach maximises the effect of the exosomes and delivers a stronger regenerative result.
To further amplify results, the treatment is often included in a wider protocol:
- with Morpheus8 for deeper stimulation and skin tightening
- with the CO2 Smaxel laser for intensive renewal of texture
- with Candela Nordlys for pigmentation and vascular irregularities
- with HIFU for lifting and action on the SMAS layer
- with PRP and Angel PRP (Arthrex) for additional growth-factor stimulation
- with polynucleotides for long-term dermal regeneration
Combinations are always tailored to the skin — never the other way around.
Who is the treatment for?
This combination is particularly indicated for:
- skin with pronounced dehydration and loss of quality
- fine lines and early signs of ageing
- enlarged pores and uneven texture
- acne scars
- skin exposed to chronic stress and photoageing
- patients who want a visible but natural result without volumisation
Ideal for those who feel their skin “doesn’t respond like it used to” — and needs a deeper regenerative boost.
When are results visible?
The first effect (freshness, hydration, glow) is visible relatively quickly.
But the real result comes gradually, through:
- fibroblast activation
- collagen synthesis
- regeneration of dermal tissue
Over time the skin becomes:
- smoother
- firmer
- more even
- more resilient
Recovery and precautions
After the treatment, the following are possible:
- redness
- sensitivity
- mild swelling
Recovery is short — typically 1–3 days.
We recommend:
- avoiding sun exposure and using SPF
- avoiding active products for a few days
- avoiding sauna, exercise and heat for 24–48 hours
Preparing for the treatment
Before the treatment a topical anaesthetic cream is applied to make the procedure as comfortable as possible.
We recommend:
- not consuming alcohol before the treatment
- avoiding medications that increase the tendency to bruise
- arriving without active inflammatory processes on the skin
Our approach
At our clinic this kind of treatment isn’t simply a procedure — it’s part of an individually guided dermatological strategy.
Treatments are delivered by experienced dermatology specialists, with detailed assessment and planning.
We offer patients what is most rare today —
time, knowledge and full dedication.
Because a sense of confidence doesn’t come from marketing — it comes from the experience the patient has from their very first visit.
