Hair loss is not simply a problem of the follicles — it is also a question of scalp quality.
When microcirculation is compromised, regeneration is reduced, and the dermal matrix is weakened, follicles gradually lose their function.
Mastelli Plinest Hair® represents an advanced therapy based on polynucleotides (PN-HPT® technology) — biologically active molecules that act at the cellular level of regeneration.
Polynucleotides are high-purity DNA fragments that:
- stimulate fibroblasts
- promote tissue regeneration
- improve microcirculation
- exert anti-inflammatory and antioxidant effects
This creates an optimal environment for:
- follicle activation
- strengthening of the hair shaft
- stimulating hair growth
The result is not immediate — rather, it is a biologically driven, gradual and long-lasting growth of healthier hair.
At our clinic, Plinest Hair® is not a form of “mesotherapy” — it is a next-generation regenerative scalp therapy.
How is the treatment performed?
The treatment is performed by administering the Plinest Hair® preparation into the scalp via intradermal microinjections.
The preparation acts on:
- the dermal papilla
- follicular cells
- the extracellular matrix
This leads to:
- stimulation of angiogenesis (improved blood supply)
- increased delivery of oxygen and nutrients
- activation of regenerative processes
Polynucleotides improve tissue quality and create the biological conditions for hair growth, rather than merely producing a short-term effect.
For optimal results, the treatment is frequently combined with:
- Angel PRP (Arthrex) for additional growth factor stimulation
- exosomes for advanced cellular regeneration
- scalp mesotherapy for nutritional support
- low-level laser therapy for follicle stimulation
- dermatologist-guided topical therapies
Who is the treatment for?
Plinest Hair® is ideal for individuals who notice:
- increased hair shedding
- thinning of the hair shaft
- loss of density
- diminished hair quality
- an irritated or dehydrated scalp
It is particularly suited to:
- early-stage androgenetic alopecia
- stress-induced hair loss
- seasonal hair shedding
- patients following hair transplantation
When are results visible?
Results develop progressively:
- first effect → reduction in shedding
- within a few weeks → strengthening of the hair shaft
- within a few months → increased density
Visible results often become apparent within a few weeks, though the full benefit requires continuity of treatment.
Recovery and precautions
The treatment involves minimal downtime.
Possible side effects include:
- mild redness
- scalp sensitivity
- small puncture marks at the injection sites
It is recommended to:
- avoid washing your hair for 24 hours
- refrain from exercise on the day of treatment
- avoid sun exposure and heat for a short period
Preparing for the treatment
Before the treatment:
- arrive with a clean scalp
- ensure adequate hydration
- avoid alcohol
If required, a topical anaesthetic cream may be applied.
Our approach
At our clinic, scalp therapies are never one-size-fits-all.
Plinest Hair® treatments are carried out by experienced consultant dermatologists, with:
- a precise diagnosis of the cause of hair loss
- an individualised treatment plan
- a combination of regenerative methods
We offer our patients what matters most:
- clarity
- safety
- ongoing monitoring
Because hair growth is not a swift process — it is a biological regeneration that demands time and expertise.
