Treatment overview
In aesthetic dermatology, there is a clear shift — away from treatments that merely “correct” appearance, towards those that restore the skin from within. This is precisely where Rejuran polynucleotides stand — one of the most advanced bioregenerative treatments available today.
Rejuran is a therapy based on polynucleotides (PN) — highly purified DNA fragments, most commonly derived from salmon, which are exceptionally compatible with human skin and carry strong regenerative potential.
Unlike fillers or conventional skin boosters, Rejuran does not add volume — instead, it acts at the cellular level, stimulating:
- renewal of damaged cells
- production of collagen and elastin
- improved microcirculation
- reduction of inflammatory processes
The result is not an “instant transformation” — rather, a gradual improvement in skin quality: the skin becomes denser, more elastic, and more resilient.
Originating from South Korea, Rejuran has been one of the most sought-after treatments in Asian aesthetics for years — a market where the focus is firmly on naturally healthy, long-term skin quality.
Patients frequently present with a sense that their skin looks “tired”, thin, or lacking vitality — even when there are no pronounced wrinkles.
This is the moment when the skin loses its “strength”, and the face no longer reflects the energy and freshness one feels.
In everyday situations — without make-up, in photographs, or in person — it is precisely this quality of the skin that makes the difference between a tired and a healthy appearance.
Rejuran does not change the face — it restores the skin’s capacity to renew itself, which is the most natural form of rejuvenation.
REJURAN EYE (Rejuran Eye) – FOR DARK CIRCLES AND DELICATE SKIN AROUND THE EYES
The area around the eyes is one of the most demanding:
- the skin is thinner
- it loses collagen more rapidly
- it is the first to show signs of fatigue and ageing
For this reason, Rejuran I (Eye) was developed — specifically formulated for this area.
What makes it distinctive:
- it has a lighter and finer consistency — adapted to thin skin
- it stimulates collagen production and skin thickening
- it improves microcirculation and hydration
Results:
- reduction of dark circles
- less visible fine lines
- firmer and “denser” skin
- a fresher, more rested appearance
Rejuran Eye → for thin, fatigued, and damaged skin around the eyes
“For dark circles, we do not seek volume — we seek skin quality.”
REJURAN S – FOR SCARS AND UNEVEN TEXTURE
With scars (particularly those caused by acne), the issue is not merely superficial — it is structural.
For this reason, Rejuran S was developed — a denser formulation that acts directly on:
- scar tissue
- irregular texture
- damaged dermal structure
How it works:
- stimulates cellular regeneration
- activates fibroblasts → collagen production
- “repairs” the skin’s structure from within
Rejuran S:
- does not fill scars like a filler
- instead, it gradually remodels and softens them
Results:
- smoother skin surface
- reduced visibility of scars
- a more even complexion
- long-term improvement in skin quality
Rejuran S → for scars and irregular skin texture.
“For scars, we do not seek concealment — we seek regeneration.”
How is the treatment performed?
The treatment is carried out via microinjections of polynucleotides into the mid-layer of the skin.
During the procedure:
- the condition and quality of the skin are assessed
- treatment zones are defined
- the preparation is applied evenly to the targeted area
The procedure is precise and minimally invasive.
Who is the treatment for?
The treatment is ideal for those who:
- notice a loss of skin quality (not necessarily volume)
- have thin, sensitive, or damaged skin
- wish to take a natural anti-ageing approach
- are looking for long-term skin regeneration
It is particularly effective for:
- fine lines
- scars (e.g. from acne)
- enlarged pores
- uneven skin tone
Our approach
Rejuran is an exceptionally sophisticated treatment — yet its true value depends on the correct indication.
At our clinic, we do not use it as a trend — but as a precisely selected therapy when genuine skin regeneration is the goal.
We assess:
- skin thickness
- degree of damage
- biological regenerative potential
Only then do we define a plan.
We frequently combine it with other biostimulative treatments — because the skin does not require a single solution, but a strategy.
Patients most commonly notice that their skin looks:
- denser
- healthier
- more resilient
…yet without looking “treated”.
Preparing for the treatment
Prior to the treatment, the following is recommended:
- arrive with clean skin
- avoid aggressive treatments for several days beforehand
- inform your doctor of any current medication or therapy
A topical anaesthetic cream is applied where required.
Recovery and precautions
Recovery is minimal, though specific.
Following the treatment:
- small papules (minor raised spots) may appear
- mild redness
This is an expected response and typically resolves within a few days.
Recommendations:
- avoid sun exposure and use SPF
- do not apply aggressive skincare products
- follow your doctor’s instructions
When are results visible?
Results develop gradually.
- initial effects within 2–3 weeks
- full results over several months
Results:
- improved elasticity
- smoother texture
- healthy and natural-looking skin
Treatment combinations
For maximum regenerative effect:
- Morpheus8 — for collagen stimulation
- CO2 Smaxel — for regeneration and texture
- Candela Nordlys — for pigmentation and skin tone quality
- HIFU — for lifting
- Icoone Laser Med — for microcirculation
Additionally:
- PRP treatments
- exosomes
- skin boosters
All combinations are planned individually — depending on the condition of the skin.
