Signature SkinPen + biorevitalisation

There are moments when the skin doesn’t need correction — it needs to come back into balance.

It isn’t about volume.
It’s about quality.

The Signature combination of SkinPen microneedling and biorevitalisation is designed exactly for those situations — when we want to trigger natural skin regeneration while at the same time providing the active ingredients needed for renewal.

SkinPen activates the process of controlled micro-trauma and neocollagenesis, while biorevitalisation cocktails (most often based on hyaluronic acid, amino acids and vitamins) act on hydration, cellular metabolism and renewal of the dermis.

The result isn’t just better-looking skin — it’s skin that functions better again.

This combination is particularly powerful on skin that has lost its glow, elasticity and ability to retain moisture — when stimulation alone is no longer enough.


How is the treatment performed?

The treatment begins with SkinPen microneedling, creating precisely controlled micro-perforations in the epidermis and dermis.

This triggers:

  • activation of fibroblasts
  • synthesis of collagen and elastin
  • remodelling of the extracellular matrix

The biorevitalisation product is then applied; it penetrates the skin via the microchannels and acts on:

  • deep hydration
  • renewal of dermal structure
  • improved cellular function

This sequential approach delivers better bioavailability of the active ingredients and a stronger therapeutic effect.

For optimal results, the treatment is often combined with:

  • Morpheus8 for additional stimulation and skin firming
  • CO2 Smaxel laser for regeneration and texture
  • Candela Nordlys for pigmentation and skin tone quality
  • HIFU for lifting and action on deeper layers
  • PRP and Angel PRP (Arthrex) for a regenerative effect
  • exosomes for advanced biological stimulation
  • polynucleotides for long-term renewal of the dermis

Who is the treatment for?

This combination is ideal for patients who notice:

  • dehydration and loss of skin elasticity
  • tired, “lifeless”-looking skin
  • fine lines and the early signs of ageing
  • compromised texture and tone
  • skin that responds less well to classical treatments

Particularly suited to those who want:

  • a natural, subtle result
  • improved skin quality without volumisation
  • a combination of hydration and regeneration

When are results visible?

The first effect is visible relatively quickly:

  • hydration
  • freshness
  • a subtle glow

But the real result comes gradually, through:

  • regeneration of the dermis
  • collagen synthesis
  • improved skin structure

Over time the skin becomes:

  • more elastic
  • smoother
  • more even
  • more resilient

Recovery and precautions

After the treatment, the following are possible:

  • redness
  • sensitivity
  • mild swelling

Recovery is short — typically 1–2 days.

We recommend:

  • avoiding sun exposure and using SPF
  • avoiding active products for a few days
  • avoiding heat, sauna and exercise for 24–48 hours

Preparing for the treatment

Before the treatment a topical anaesthetic cream is applied to make the procedure as comfortable as possible.

We recommend:

  • avoiding alcohol before the treatment
  • avoiding medications that increase the tendency to bruise
  • arriving without active inflammatory processes on the skin

Our approach

At our clinic biorevitalisation isn’t an “add-on” — it’s part of an individually planned dermatological approach to skin regeneration.

Treatments are delivered by experienced dermatology specialists, with detailed analysis and a personalised therapy plan.

We give patients what makes a real difference in aesthetic medicine:

  • professional guidance
  • time to understand the skin
  • therapy tailored to their needs

Because skin quality doesn’t come from a single treatment — it comes from the right approach.

Price: 

For detailed information on payment options and treatment prices, please refer to the current price list of Poliklinika dr. Jelena Jakić.

Contact Us

Have a question? Send us an enquiry and we will be happy to respond.

    Need Help?

    Our team of specialists is at your disposal for all information and advice.
    Phone

    +385 1 2365 953
    +385 91 9117 093

    Email

    info@poliklinika-jakic.hr

    FAQ

    Frequently asked questions

    Here you’ll find answers to the questions our clients most often ask about our services and treatments.

    + What is biorevitalisation and how does it work in combination with microneedling?
    Biorevitalisation involves the application of hyaluronic acid and other active ingredients for deep hydration and skin renewal. Combined with SkinPen microneedling, these ingredients are absorbed more deeply and effectively.
    + What are the main effects of this treatment?
    Increased hydration, better elasticity, more even texture and an overall healthier look. The skin appears fresher and “fuller” without adding volume.
    + Which skin condition is it best suited to?
    Dehydrated, thin and tired skin, as well as the early signs of ageing.
    + When are results visible?
    First results are visible right after the treatment, while the full effect develops over several sessions.
    + How many treatments are needed?
    A series of treatments is recommended, adjusted to your individual skin condition and goals.
    + Is the treatment painful?
    Minimally uncomfortable, with a topical anaesthetic cream applied beforehand.
    + Why is this combination becoming increasingly popular?
    Because it delivers a natural “glow effect” with a real improvement in skin quality — a combination patients are increasingly looking for.